Angela E Hawley Selected Research

2- (4- chlorobenzyl)- 3- hydroxy- 7,8,9,10- tetrahydrobenzo(H)quinoline- 4- carboxylic acid

3/2007	Resolution of venous thrombosis using a novel oral small-molecule inhibitor of P-selectin (PSI-697) without anticoagulation.
9/2006	Treatment with an oral small molecule inhibitor of P selectin (PSI-697) decreases vein wall injury in a rat stenosis model of venous thrombosis.
8/2005	Decreased venous thrombosis with an oral inhibitor of P selectin.

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Angela E Hawley Research Topics

Disease

25	Thrombosis (Thrombus) 01/2017 - 11/2002
18	Venous Thrombosis (Deep-Vein Thrombosis) 01/2017 - 11/2002
7	Inflammation (Inflammations) 09/2014 - 06/2003
5	Fibrosis (Cirrhosis) 04/2015 - 11/2002
2	Hemorrhage 01/2017 - 01/2017
2	Venous Thromboembolism 01/2017 - 09/2002
1	Sudden Infant Death (SID) 01/2017
1	Stroke (Strokes) 01/2017
1	Hyperlipidemias (Hyperlipidemia) 03/2012
1	Pain (Aches) 06/2010
1	Pathologic Constriction (Stenosis) 09/2006
1	Necrosis 09/2002
1	Pulmonary Embolism 09/2002

Drug/Important Bio-Agent (IBA)

19	P-SelectinIBA 04/2015 - 09/2002
10	Proteins (Proteins, Gene)FDA Link 03/2015 - 06/2003
6	Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA 01/2017 - 11/2002
5	fibrin fragment D (D-dimer)IBA 06/2013 - 12/2005
5	Thromboplastin (Tissue Factor)IBA 05/2011 - 11/2002
4	E-SelectinIBA 01/2017 - 09/2002
4	Enoxaparin (Lovenox)FDA LinkGeneric 01/2017 - 02/2008
4	EnzymesIBA 09/2006 - 11/2002
4	ImmunosorbentsIBA 09/2006 - 11/2002
3	SelectinsIBA 01/2017 - 11/2003
3	Interleukin-6 (Interleukin 6)IBA 03/2015 - 02/2011
3	LigandsIBA 03/2015 - 08/2005
3	CytokinesIBA 09/2014 - 09/2002
3	Interleukin-10 (Interleukin 10)IBA 09/2014 - 09/2002
3	Messenger RNA (mRNA)IBA 10/2012 - 06/2003
3	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 03/2012 - 06/2003
3	2- (4- chlorobenzyl)- 3- hydroxy- 7,8,9,10- tetrahydrobenzo(H)quinoline- 4- carboxylic acidIBA 03/2007 - 08/2005
2	von Willebrand FactorIBA 04/2015 - 08/2010
2	Tissue Plasminogen Activator (Alteplase)FDA Link 06/2013 - 03/2012
2	Plasminogen Activators (Plasminogen Activator)IBA 03/2012 - 01/2010
2	ChemokinesIBA 02/2011 - 09/2002
2	Hemostatics (Antihemorrhagics)IBA 06/2010 - 03/2009
1	Factor Xa InhibitorsIBA 01/2017
1	uproleselanIBA 01/2017
1	apixabanIBA 01/2017
1	Warfarin (Coumadin)FDA LinkGeneric 01/2017
1	ARC5692IBA 04/2015
1	ARC15105IBA 04/2015
1	Galectin 3 (LGALS3)IBA 03/2015
1	Buprenorphine (Subutex)FDA LinkGeneric 09/2014
1	Analgesics (Analgesic Drugs)IBA 09/2014
1	Bupivacaine (Bupivacaine Hydrochloride)FDA LinkGeneric 09/2014
1	Fibrinolytic Agents (Antithrombotic Agents)IBA 06/2013
1	Fibrinolysin FDA Link 06/2013
1	Immunoglobulin G (IgG)IBA 10/2012
1	ApolipoproteinsIBA 03/2012
1	Matrix Metalloproteinases (MMPs)IBA 03/2012
1	Apolipoproteins E (ApoE)IBA 03/2012
1	Plasminogen Activator Inhibitor 1IBA 03/2012
1	Urokinase-Type Plasminogen Activator (Urokinase)FDA Link 03/2012
1	Biomarkers (Surrogate Marker)IBA 08/2011
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 05/2011
1	Blood Proteins (Serum Proteins)IBA 06/2010
1	Immunoglobulins (Immunoglobulin)IBA 03/2009
1	Fibrinogen (Factor I)FDA Link 03/2009
1	Membrane Proteins (Integral Membrane Proteins)IBA 03/2009
1	enoxaparin sodium FDA LinkGeneric 02/2008
1	PSI-421IBA 02/2008
1	AntibodiesIBA 08/2005
1	InterleukinsIBA 08/2005
1	CollagenIBA 08/2003
1	AnticoagulantsIBA 11/2002
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 09/2002

Therapy/Procedure

6	Ligation 09/2014 - 11/2002
4	Therapeutics 01/2017 - 08/2005
1	Diet Therapy (Therapy, Diet) 01/2017
1	Injections 04/2009
1	Aftercare (After-Treatment) 08/2003
1	Thrombolytic Therapy 11/2002